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Hermatology primeFISH Products

HEMATOLOGY

PANEL

17-054 del(7q31.2)

Chromosome 7 monosomy and deletion of the long arm of (AML), and juvenile myelomonocytic leukemia (JMML).
chromosome 7 are recurrent chromosomal abnormalities The pres ence of Monosomy 7 or del (7q) as karyotypic
frequently seen in myeloid diseases. Monosomy 7 and changes is associated with worse out comes in myeloid
de1(7q); it is seen in many myeloid diseases, including malignancies.
myelodysplastic syndrome (MDS), acute myeloid leukemia

DELETION

D7Z1
(7p11.1-q11.1) NORMAL

D7S486 STSG597801 DELETION
3' 5'
7q31.2 Gen Tel
TES
358 kb

(Not to scale)

www.diagen.com.tr References
Fisher et al., Blood 1997;89(6):2036-2041
Arsham, MS., Barch, MJ. and Lawce HJ. (eds.) (2017) The AGT Cytogenetics Laboratory Manual. New Jersey: John Wiley & Sons Inc.
Trobaugh-Lotrario et al., Bone Marrow Transplantation 2005;35(2):143-149

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