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Hematology primeFISH Products
HEMATOLOGY
PANEL
17-054 del(7q31.2)
Chromosome 7 monosomy and deletion of the long arm of
chromosome 7 are recurrent chromosomal abnormalities
frequently seen in myeloid diseases. Monosomy 7 and
de1(7q); it is seen in many myeloid diseases, including
myelodysplastic syndrome (MDS), acute myeloid leukemia
(AML), and juvenile myelomonocytic leukemia (JMML).
The presence of Monosomy 7 or del (7q) as karyotypic
changes is associated with worse out comes in myeloid
malignancies.
DELETION
D7Z1
(7p11.1-q11.1) NORMAL
D7S486 STSG597801
Cent Tel
TES
358 kb DELETION
7q31.2
(Not to scale)
www.diagen.com.tr References
Fisher et al., Blood 1997;89(6):2036-2041
Arsham, MS., Barch, MJ. and Lawce HJ. (eds.) (2017) The AGT Cytogenetics Laboratory Manual. New Jersey: John Wiley & Sons Inc.
Trobaugh-Lotrario et al., Bone Marrow Transplantation 2005;35(2):143-149
8 PRODUCT CATALOGUE
